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Herbs-Ex Inc

Diosmin
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DIOSMIN EP4

DIOSMIN ACTION MECHANISM

Diosmin is a veinotropic agent and vasculoprotective compound which increases the capillary resistance of blood vessels, increases vein tonicity and decreases capillary permeability. Diosmin has an anti-inflammatory activity related to an inhibition of prostaglandin synthesis. used to treat chronic venous insuficiency, hemorrhoids, lymphedema, and varicose veins. Diosmin is also a powerful antiinflammatory and free-radical scavenging agent. Diosmin should also be used for dermatitis and wound healing.
Diosmin has been used for more than 30 years as a vein tonic and vascularprotecting agent. It is now being researched for cancer, premenstrual syndrome, colitis, and diabetes.
Diosmin improves vein tone, increases lymphatic drainage, protects capillaries, inhibits inflammation, and reduces capillary fragility and permeability.

INGREDIENT MANUFACTURING PROCESS

Diosmin is a naturally occurring flavonoid glycoside isolated from various plants and the flavonoid hesperidin. Hesperidin is extracted and isolated from orange or lemon rinds, . The hesperidin is then converted to Diosmin using a proprietary procedure. The remaining product is 92% - 95% Diosmin and 5% - 8% "free" hesperidin. Diosmin differs from hesperidin by the absence of a double bond between two carbon atoms (C2-C3).
SPECIFICATIONS
Botanical Source: Citrus Aurantium L.
Molecular Formula:C28H32O15
Molecular Weight: 608.55
CAS:520-27-4
Diosmin: HPLC90-102%
Total Impurity: HPLC10% Max
Acetoisovanillone: 1% Max
Hesperidin: 5% Max
Isorhoifolin: 3% Max
Linarin: 3% Max
Diosmitin: 3% Max
Other impurity: 2% Max

Dosage: Diosmin (micronized) 300 mg/Capsule, 3 capsules daily with food or as directed by a health practitioner.

Contact Details
Contact Person (Department): Mr. Mr. Kingsing Guan     
Company Address: 3/F, Blding C1, Kemulang Industry Park, 98 Guangshan 2nd Road,
City/Town: Guangzhou
Province/State: Guangdong
Country/Region: China
Zip/Postal Code: 510520
Phone Number: 86 133 80023492
Fax Number: 86 20 87026237
Homepage: www.herbs-ex.com

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